Tamper Evident Pill Box Labels for Secure Pharmaceutical Packaging

Tamper Evident Pill Box Labels, specifically engineered for pill boxes, medication cartons, and blister packs

Custom security labels for medicine packaging, trusted by pharmacies, hospitals and pharmaceutical manufacturers.

Why You Need Tamper Seals for High Risk Packaging

Tamper evident pill box labels are specially designed to protect medicine packaging from unauthorised access or interference. These labels make any attempt to open, alter or re-close a box immediately visible, helping to ensure product integrity, compliance with global regulations, and the safety of patients.

From Hospital Trusts and community pharmacies to contract repackaging companies and clinical trial suppliers, tamper evident labelling is increasingly seen as essential — not optional. The consequences of even minor packaging breaches in the pharmaceutical supply chain can be serious: regulatory risk, patient harm, brand damage and costly recalls.

TamperTech manufactures these labels in the UK to meet the unique requirements of medicine handling, offering fully customisable formats suitable for manual use and automatic application systems.

Voided Small Pill Box Paper Tamper-Evident Label - 25mm x 12mm for Pharmaceuticals

Why tamper evident labels are essential for pharma

Global pharmaceutical packaging regulations, including MHRA guidance, US FDA guidance, the EU Falsified Medicines Directive (FMD), and ISO 21976, all highlight the need for packaging that visibly shows signs of tampering.

Tamper evident pill box labels support:

  • Prevention of counterfeit substitution or theft

  • Compliance with national and international regulatory standards

  • Enhanced patient safety and trust

  • Controlled drug repackaging accountability

  • Visual audit trails for pharmacy or QA inspection

  • Secure logistics between manufacturing, warehousing and delivery points

Tamper evidence is now a central part of the overall pharmaceutical packaging design process, particularly for high-risk or high-value medicines, and those used in care homes, hospitals, and remote patient delivery.

Product specifications

TamperTech’s labels are engineered for demanding use cases in both manual and automated packaging environments, including cold chain handling.

Material options:

  • VOID polyester

  • Destructible vinyl

  • Gloss or matt finish

  • Paper or Filmic

Adhesive types:

  • Permanent adhesive

  • High-tack for rough or recycled surfaces

  • Freezer-grade for cold chain packaging

  • Clean-peel for no residue clinical use

Label features:

  • Custom colour print

  • Serialisation, barcodes, QR codes

  • Perforated tear or frangible design

  • Custom shapes for pill boxes and blister packs

  • Tamper response: Unique VOID message, surface transfer or destruction

Application methods:

  • Easy hand application in pharmacy or packaging lines

  • Compatible with automatic labelling machines and pill box applicators

  • Supplied on rolls, sheets or fanfold formats

TamperTech supports application testing and setup for automated machinery to reduce downtime and speed up integration.

Image of Small Pill Box Paper permanent tamper evident label 25mm x 12mm, applied and removed showing the Void message for Pharmaceuticals

Common use cases

Tamper evident pill box labels are used across the pharmaceutical sector:

  • Hospital pharmacy units for inpatient and outpatient medication

  • Community pharmacy repackaging for care homes and MAR charts

  • Online pharmacy e-commerce orders and home delivery

  • Contract repackers and fulfilment companies

  • Clinical trial sample kits and blinded studies

  • Veterinary medicine packaging

  • High-risk controlled drug repackaging

Each of these sectors faces different pressures, from medication tampering and theft prevention, to logistics traceability and patient trust. Labels are tailored for performance in each scenario.

pill box label VOID opened on box

Case Study: Contract Packager Cuts Downtime and Improves Compliance with Automated Tamper Labels

A leading pharmaceutical contract packaging company working with major OTC and prescription drug brands was facing growing pressure from its clients to enhance tamper evidence across multiple lines of pill box and blister pack formats.

The company needed a tamper evident labelling solution that could:

  • Integrate seamlessly with their existing high-speed automatic labelling equipment

  • Be customised to fit multiple pill box and carton sizes

  • Comply with MHRA and EU Falsified Medicines Directive requirements

  • Minimise downtime during roll changes and avoid machine jams

  • Offer visual proof of tampering without damaging critical packaging data like batch codes or expiry dates

TamperTech collaborated directly with their engineering and compliance teams to design a custom VOID polyester label, optimised for their specific packaging lines. The label included:

  • Precision die-cutting to ensure perfect application

  • Freezer-grade adhesive suitable for both ambient and cold chain products

  • Unique VOID transfer tamper evidence

  • Machine compatible roll format with core and unwind direction tailored to their applicators

  • Optional serialisation and barcode printing for future-proofed compliance

Results after rollout:

  • Zero machine stoppages during 1.2 million labels applied over the first few months roll out.

  • Changeover time between runs reduced by 40%

  • Audit-ready labelling that passed client QA checks and third party inspections

  • Flexible inventory use across multiple product lines and formats

  • Positive feedback from two of their biggest customers, who later expanded their contracts

With TamperTech’s support, the packager gained a competitive advantage, offering tamper-evident compliance without adding bottlenecks or operational risk.

Why TamperTech?

  • Two decades of tamper evident innovation

  • ISO 9001, UN ADR, and FSMA compliance

  • Rapid prototyping and global supply

  • Rapid customisation and UK-based production

  • Experts in compliant, scalable packaging design

  • ISO-certified and regulation-aligned

Certifications: ISO 9001 | ISO 45001 | ISO 27001 | ECO VADIS | EU MDR-Ready

Customisation options

  • Custom colours and messages

  • Brand logos and batch trace codes

  • Serialized QR or barcode printing

  • Multilingual warnings and regulatory icons

  • FSC-certified paper and eco materials available

Let’s help you make risk visible and prevent the preventable.

📞 Contact: Ciara or Harriet | 📧 harriet@tampertech.com | +44 1335 300335

Let's secure your products together